[8-(Dialkylamino alkoxy)-caffeine]-platinum complex compounds an

Details [8-(Dialkylamino alkoxy)-caffeine]-platinum complex compounds an [8-(Dialkylamino alkoxy)-caffeine]-platinum complex compounds an

1981-12-04

1983-11-22

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

544225, 424251, A61K 31515, C07D47312

Patent

active

044168780

ABSTRACT:
New [8-(dialkylamino alkoxy)-caffeine]-platinum complex compounds of the general formula ##STR1## are prepared from 8-(dialkylamino alkoxy)-caffeine and hexachloro platinic acid. The complex compounds are nonpoisonous, stable and infinitely durable. In pharmacological test series distinct cytostatic activity of the complex compounds is observed and they are suitable for use as active components in pharmaceutical products.

REFERENCES:
patent: 3794648 (1974-02-01), Hammond et al.
patent: 4080324 (1978-03-01), Hoeschelk
Melnik, "J. Inorg. Chem." vol. 43, No. 11, 1981, pp. 3035-3038.
Rosenberg, et al. "Nature," vol. 222, 4/26/69, pp. 385-386, Cleare, "Coordination Chemistry Reviews," vol. 12, 1974, pp. 349-405.

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