8-chlorodibenz[b,f][1,4]oxazepine-10-(11H)-carboxylic acid, 2-[(

Details 8-chlorodibenz[b,f][1,4]oxazepine-10-(11H)-carboxylic acid, 2-[( 8-chlorodibenz[b,f][1,4]oxazepine-10-(11H)-carboxylic acid, 2-[(

1986-11-14

1987-07-21

Milestone, Norma S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Unsubstituted hydrocarbyl chain between the ring and the -c-...

C07D26720

Patent

active

046819398

ABSTRACT:
This invention relates to 8-chlorodibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid, 2-[(substituted phenylsulfinyl)alkanoyl]hydrazides and 8-chlorodibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid, 2-[(substituted phenylsulfonyl)alkanoyl]hydrazides that are useful as prostaglandin antagonists and analgesic agents. This invention also relates to 8-chlorodibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid, 2-[(substituted phenylthio)alkanoyl]hydrazides that are useful as intermediates in the preparation of the corresponding sulfinyl and sulfonyl compounds.

REFERENCES:
patent: 3534019 (1970-10-01), Coyne et al.
patent: 3917649 (1975-11-01), Mueller
patent: 3989719 (1976-11-01), Mueller
patent: 3992375 (1976-11-01), Mueller
patent: 4045442 (1977-08-01), Mueller
patent: 4125532 (1978-11-01), Mueller
patent: 4170593 (1979-10-01), Mueller

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