8-(.beta.-AMINOETHYL)ERGOLINES-I

Details 8-(.beta.-AMINOETHYL)ERGOLINES-I 8-(.beta.-AMINOETHYL)ERGOLINES-I

1975-03-19

1977-01-25

Gallagher, R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424261, C07D45702

Patent

active

040050904

ABSTRACT:
8-(.beta.-AMINOETHYL)ERGOLINES-I of the general formula ##STR1## wherein R.sup.1 is a hydrogen atom or an acyl group of the general formula R.sup.3 --CO, R.sup.3 being a hydrogen atom, an alkyl group having from 1-5 carbon atoms, a phenyl group, a phenylalkyl group or a pyridyl group or substituents thereof, and R.sup.2 is a hydrogen atom or a methyl group. Acid addition salts of the described ergolines evidence pharmacological activity in the anti-inflammation and hypotensive fields.

REFERENCES:
patent: 3557118 (1971-01-01), Arcamone et al.
patent: 3646046 (1972-02-01), Arcamone et al.
Bernardi et al.; Gazz. Chem. Ital; vol. 24, pp. 936-978 (1964).
Morrison et al.; Organic Chemistry 2nd Edition; (1969) pp. 728, 741.
Bernardi et al.; Chem. Abst. vol. 60; 10739d, (1963).

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