8.beta.,12.alpha.-PGE.sub.2 -type compounds

Details 8.beta.,12.alpha.-PGE.sub.2 -type compounds 8.beta.,12.alpha.-PGE.sub.2 -type compounds

1973-06-28

1978-07-11

Gerstl, Robert

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

260514D, 560231, C07C17700

Patent

active

041003551

ABSTRACT:
This invention is a group of 8-beta, 12-alpha-PG.sub.2 (prostaglandin-type) analogs having variable chain length, or methyl or phenyl substitution in the hydroxy-substituted side-chain, and processes for making them. These compounds are useful for a variety of pharmacological purposes, including anti-ulcer, inhibition of platelet aggregation, increase of nasal patency, and labor inducement at term.

REFERENCES:
corey et al., J.O.C. 37, 3043 (1972).
Gandolfi et al., Tet. Letters, 4303 (1972).

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