8.beta.,11.beta.,12.alpha.-PGF.sub.2.sub..alpha. compounds

Details 8.beta.,11.beta.,12.alpha.-PGF.sub.2.sub..alpha. compounds 8.beta.,11.beta.,12.alpha.-PGF.sub.2.sub..alpha. compounds

1974-10-29

1976-10-19

Gerstl, Robert

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260240R, 2603433R, 2603462R, 260348A, 260488R, 260473A, 260514D, 260514K, 260521R, 260303, 260308, 260317, C07C17700

Patent

active

039870855

ABSTRACT:
This invention is a group of 8-.beta., 12-.alpha.-PG.sub.2 (prostaglandin-type) analogs having variable chain length, or methyl or phenyl substitution in the hydroxy-substituted side-chain, and processes for making them. These compounds are useful for a variety of pharmacological purposes, including anti-ulcer, inhibition of platelet aggregation, increase of nasal patency, and labor inducement at term.

REFERENCES:
patent: 3812179 (1974-05-01), Bundy
patent: 3862984 (1975-01-01), Pike et al.

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