Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1974-10-29
1976-07-13
Gerstl, Robert
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
260211R, 2602472R, 260268R, 26029365, 2603262, 2604299, 260439R, 260448R, 2605011, 26050115, 26050117, 2605012, 260514D, C07C17700
Patent
active
039693961
ABSTRACT:
This invention is a group of 8-beta, 12-alpha-PG.sub.2 (prostaglandin-type) analogs having variable chain length, or methyl or phenyl substitution in the hydroxy-substituted side-chain, and processes for making them. These compounds are useful for a variety of pharmacological purposes, including anti-ulcer, inhibition of platelet aggregation, increase of nasal patency, and labor inducement at term.
REFERENCES:
patent: 3812179 (1974-05-01), Bundy
patent: 3862984 (1975-01-01), Pike et al.
Ferdinand et al., Can. J. Chem. 49, 1070, (1971).
Armitage Robert A.
Gerstl Robert
Nielsen Morris L.
The Upjohn Company
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