Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1976-03-01
1977-05-31
Daus, Donald G.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
2602564F, C07D48704, A61K 3141
Patent
active
040270254
ABSTRACT:
9-Hydroxyethoxymethyl (and related) derivatives of 2-amino-6-substituted-8-azapurines have been found to have potent anti-viral activities. Novel compounds and their pharmaceutically acceptable salts, pharmaceutical formulations containing the compounds of this invention, and the treatment of viral infections with these formulations are all disclosed. 9-(2-Hydroxyethoxymethyl)-8-azaguanine and 9-(2-benzoyloxyethoxymethyl)-8-azaguanine are examples of active compounds of this invention.
REFERENCES:
patent: 2407204 (1946-09-01), English et al.
patent: 3819631 (1974-06-01), Broughton et al.
patent: 3836656 (1974-09-01), Buzzolini
Schaeffer, "J. Med. Chem.," vol. 14, No. 4, 1971, pp. 367-369.
Schaeffer, et al., "J. Pharm. Sci.," vol. 60, No. 8, 1971, pp. 1204-1209.
Lerner, et al., "Biochemistry," vol. 11, No. 15, 1972, pp. 2772-2777.
Davoll, "J. Chem. Soc.," 1958, pp. 1593-1599.
Brown Donald
Burroughs Wellcome Co.
Daus Donald G.
Turnipseed James H.
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