8-azaprostaglandin derivative compounds and drugs containing...

Details 8-azaprostaglandin derivative compounds and drugs containing... 8-azaprostaglandin derivative compounds and drugs containing...

2008-07-22

2008-07-22

McKane, Joseph (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C548S551000

Reexamination Certificate

active

07402605

ABSTRACT:
An 8-azaprostaglandin represented by formula (I)(wherein all symbols have the same meanings as described in the specification), a pharmaceutically acceptable salt thereof or a cyclodextrin clathrate thereof. Since the compound represented by formula (I) binds to EP2 subtype among PGE receptor strongly, it is useful for preventive and/or treatment for immune diseases, allergic diseases, neuronal cell death, dysmenorrhea, premature birth, abortion, baldness, retinal neuropathy such as glaucoma, erectile dysfunction, arthritis, pulmonary injury, pulmonary fibrosis, pulmonary emphysema, bronchitis, chronic obstructive pulmonary disease, hepatic injury, acute hepatitis, liver cirrhosis, shock, nephritis, renal failure, circulatory diseases, systemic inflammatory response syndrome, sepsis, hemophagocytosis syndrome, macrophage activation syndrome, still disease, Kawasaki Disease, burn, systemic granuloma, ulcerative colitis, Crohn disease, hypercytokinemia at dialysis, multiple organ failure, or bone diseases etc.

REFERENCES:
patent: 5310499 (1994-05-01), Scherowsky et al.
patent: 6552067 (2003-04-01), Cameron et al.
patent: 471201 (1992-02-01), None
patent: 1110949 (2000-12-01), None
patent: 1121939 (2001-08-01), None
patent: 1132086 (2001-09-01), None
patent: 2001-181210 (2001-07-01), None
patent: 2001-220357 (2001-08-01), None
patent: 2001-233792 (2001-08-01), None
patent: WO 02/24647 (2002-03-01), None
patent: WO 02/42268 (2002-05-01), None
patent: WO 03/007941 (2003-01-01), None
patent: WO 03/008377 (2003-01-01), None
patent: WO 03/009872 (2003-02-01), None
Patani et al., Bioisosterism: A Rational Approach in Drug Design, Chem. Rev. 1996, 96, 3147-3176, especially p. 3156.

Affiliated with

Also associated with

Rating

8-azaprostaglandin derivative compounds and drugs containing... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 8-azaprostaglandin derivative compounds and drugs containing..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 8-azaprostaglandin derivative compounds and drugs containing... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2744835