8-Aza-13-thiaprostanoids and a method of use thereof as anti-ulc

Details 8-Aza-13-thiaprostanoids and a method of use thereof as anti-ulc 8-Aza-13-thiaprostanoids and a method of use thereof as anti-ulc

1982-12-27

1985-07-23

Raymond, Richard L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514926, 514925, 548543, 548547, C07D20726, A61K 3140

Patent

active

045309337

ABSTRACT:
Biologically active 8-aza-13-thiaprostanoids having the formula: ##STR1## wherein A is CH.dbd.CH (cis or trans), C.tbd.C, CH.sub.2 CH.sub.2, ##STR2## or CHOHCH.sub.2 ; R is H, C.sub.1 to C.sub.12 n-alkyl, branched chain alkyl, or cycloalkyl, or a physiologically acceptable metal or amine salt cation;

REFERENCES:
patent: 3975399 (1976-09-01), DeFranco et al.
patent: 4003911 (1977-01-01), Scribner
patent: 4032533 (1977-06-01), Scribner
patent: 4113873 (1978-09-01), Himizu et al.
patent: 4115401 (1978-09-01), Nanthavong et al.
patent: 4117346 (1979-12-01), Nelson
patent: 4209639 (1980-06-01), Wissner
patent: 4211876 (1980-07-01), Scribner
patent: 4320136 (1982-03-01), Scribner
Novak et al., Tetrahedron Letters, vol. 38, No. 1, pp. 153-159, 1982.

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