8-Arylalkyl-3-phenyl-3-nortropanols and salts thereof

Details 8-Arylalkyl-3-phenyl-3-nortropanols and salts thereof 8-Arylalkyl-3-phenyl-3-nortropanols and salts thereof

1981-11-25

1983-07-12

Fan, Jane T.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

546125, 546127, 546129, 546130, C07D40102, A61K 3146

Patent

active

043930697

ABSTRACT:
Compounds of the formula ##STR1## wherein Ar is ##STR2## R.sub.1 is hydrogen, fluorine, bromine, methyl or methoxy; X is .dbd.CO, .dbd.CH--CN, .dbd.CH--OH, --O--, --S--, --NH--, ##STR3## and R is hydrogen, 4-fluoro, 4-chloro, 4-trifluoromethyl, 3-trifluoromethyl, 3-trifluoromethyl-4-chloro, 4-methyl or 4-methoxy;
and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as their salts are useful as neuroleptics.

REFERENCES:
patent: 2921938 (1960-01-01), Wetteran
patent: 3452029 (1969-06-01), Childress et al.
patent: 3657252 (1972-04-01), Kaiser et al.

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