8-Aminoalkyl-4-alkylpsoralens

Details 8-Aminoalkyl-4-alkylpsoralens 8-Aminoalkyl-4-alkylpsoralens

1979-09-10

1981-05-26

Jiles, Henry R.

Drug, bio-affecting and body treating compositions

Nonspecific immunoeffector, per se ; or nonspecific...

Synthetic or structurally-modified peptidoglycan or...

26034321, C07D49304, A61K 31365

Patent

active

042698510

ABSTRACT:
The invention relates to 8-aminoalkyl-4-alkylpsoralens having enhanced photosensitizing activity, especially oral activity, including early onset, increased maximum, and rapid decline, as well as low toxicity, when compared with psoralens of different structure.

REFERENCES:
patent: 4124598 (1978-11-01), Hearst et al.
patent: 4169204 (1979-09-01), Hearst et al.
patent: 4217445 (1980-08-01), Nikolaiski
Hearst et al., (II), Chem. Abst. 87: 78962f, 1977.
Dawber, J. Soc. Comet. Chem., 28-403-406, 1977.
Martins et al., Chem. Abst., vol. 81, 1974, 99676g.
Shen et al., Chem. Abst., vol. 88, 88: 59494j.
Johnston et al., Chem. Abst., 87: 147284a.
Isaacs et al., Chem. Abst., 86: 135108n.

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