8-alkoxyquinolonecarboxylic acid and salts thereof

Details 8-alkoxyquinolonecarboxylic acid and salts thereof 8-alkoxyquinolonecarboxylic acid and salts thereof

1987-01-16

1990-12-25

Raymond, Richard L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

544225, 544226, 546 8, 546156, C07D40304, C07D40104

Patent

active

049804707

ABSTRACT:
Quinolonecarboxylic acid derivatives of the following formula: ##STR1## wherein R indicates a hydrogen atom or lower alkyl group, R.sup.1 indicates a lower alkyl group, R.sup.2 indicates a hydrogen atom, amino group or nitro group, X indicates a halogen atom, and Z indicates a halogen atom, piperazino group, N-methylpiperazino group, 3-methylpiperazino group, 3-hydroxypyrrolidino group, or pyrrolidino group of the following formula, ##STR2## (here, n is 0 or 1, R.sup.3 indicates a hydrogen atom or lower alkyl group, R.sup.4 indicates a hydrogen atom, lower alkyl group and R.sup.5 indicates a hydrogen atom, lower alkyl group, acyl group or alkoxycarbonyl group), the hydrates and pharmaceutically acceptable salts thereof are useful as antibacterial agents.

REFERENCES:
patent: 4665079 (1987-05-01), Culbertson et al.
patent: 4822801 (1989-04-01), Domagala et al.

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