Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1991-05-08
1994-07-26
Ramsuer, Robert W.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514287, 514288, 546 18, 546 66, 546 64, A61K 31445, C07D47114
Patent
active
053327462
ABSTRACT:
The invention relates to a group of new 8,9-annelated-.beta.-carbolines and 8,9-annelated-3,4-dihydro-.beta.-carbolines having interesting fibrinolytic properties. In particular the compounds can be used as orally active fibrinolytics.
The compounds have the general formulae 1 and 2 ##STR1## wherein R.sub.2 +R.sub.3 together with the carbon atom and the nitrogen atom to which they are bound and the intermediate carbon atom constitute a heterocyclic group consisting of 5-10 ring atoms.
REFERENCES:
patent: 4190657 (1980-02-01), Koletar
patent: 4200638 (1980-04-01), Hannart
patent: 4617305 (1986-10-01), Hannart
Haeck Hans H.
Hamminga Derk
Jansen Johannes W. C. M.
Van Wijngaarden Ineke
Duphar International Research B.V.
Haley Jacqueline
Ramsuer Robert W.
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