Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2011-05-24
2011-05-24
Moore, Susanna (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C544S252000
Reexamination Certificate
active
07947697
ABSTRACT:
8-(3-pentylamino)-2-methyl-3-(2-chloro-4-methoxyphenyl)-6,7-dihydro-5H-cyclopenta[d]pyrazolo[1,5-a]pyrimidine methanesulfonate of the structural formula (I)has Corticotropin Releasing Factor (CRF) antagonist activity and is useful in treating neuropsychiatric and digestive system diseases.
REFERENCES:
patent: 5843951 (1998-12-01), Inoue et al.
patent: 6194574 (2001-02-01), Yoon
patent: 6348466 (2002-02-01), Haddach et al.
patent: 6495686 (2002-12-01), Yoon
patent: 6514982 (2003-02-01), Haddach et al.
patent: 6531475 (2003-03-01), Haddach et al.
patent: 6723721 (2004-04-01), Haddach et al.
patent: 7034153 (2006-04-01), Nakai et al.
patent: 2004/0072833 (2004-04-01), Nakai et al.
patent: 0503099 (1992-09-01), None
patent: 0795555 (1997-09-01), None
patent: 1354884 (2003-10-01), None
patent: 5-112571 (1993-05-01), None
patent: WO 97/11946 (1997-04-01), None
patent: 99/64422 (1999-12-01), None
patent: 00/27846 (2000-05-01), None
patent: 00/27850 (2000-05-01), None
patent: WO 02/053565 (2002-07-01), None
Berge et. al. (Journal of Pharmaceutical Sciences, 1977, pp. 1-19).
Bastin et. al. (Organic Process & Development, 2000, 4, pp. 427-435).
Jones et al, “British Society of Gastroenterology guidelines for the management of the irritable bowel syndrome.” Gut 2000, (Suppl II)47:ii1-ii19).
Palmer (TRENDS in Pharmacological Sciences 23(9) 426-433).
International Search Report dated Sep. 21, 2004.
Leach, C. et al., “Reversible Inhibitors of the Gastric (H+/K+)-ATPase. 2.1-Arylpyrrolo[3,2-c]quinolines: Effect of the 4-Substituent”, J. Med. Chem., 35(10), 1845-1852 (1992).
Sivakamasundari, S. et al., “Pyrroloquinolines: PartIV†-Synthesis of 1-Aryl-1H-pyrrolo[2,3- b]quinolines”, Indian J. Chem., 26B(8), 744-747 (1987).
Smith, L et al., “A novel and highly efficient synthesis of the aza analogs of tacrine”, Tetrahedron Letters, 40, 5643-5646 (1999).
Himbert, G. et al., “Cyclisierung von N1, N2-Diaryl-N1-phenacyl-3-aminopropiolamidinen”, Liebigs Ann. Chem. 1985, 1389-1397, abstract.
Tominaga, Y. et al, “Synthesis of Methylthiomaleimides for the Preparation of Pyridazines and Related Compounds”, J. Heterocyclic Chem., 39(3), 571-591 (2002).
Araki Hiroshi
Gemba Yuichi
Hasegawa Tomoyuki
Matsui Toshiaki
Mikami Yutaka
Moore Susanna
Ono Pharmaceutical Co. Ltd.
Sughrue & Mion, PLLC
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