Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1984-01-17
1985-07-30
Daus, Donald G.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
544279, C07D47104, C07D48704, A61K 31505
Patent
active
045322414
ABSTRACT:
10-Alkyl-8,10-dideazaminopterins of the formula ##STR1## where R is hydrogen or alkyl of 1 to about 8 carbon and their carboxylate and acid addition salts are described. These compounds exhibit antineoplastic activity that is similar to, but more effective than, methotrexate.
REFERENCES:
patent: 4460591 (1984-07-01), DeGraw et al.
DeGraw Joseph I.
Kelly Lawrence F.
Sirotnak Francis M.
Daus Donald G.
Kapner Stephen
SRI - International
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