8,10-diaza-bicyclo[4.3.1]decane derivatives and their...

Details 8,10-diaza-bicyclo[4.3.1]decane derivatives and their... 8,10-diaza-bicyclo[4.3.1]decane derivatives and their...

2011-03-22

2011-03-22

Kifle, Bruck (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C540S556000

Reexamination Certificate

active

07910578

ABSTRACT:
This invention relates to novel 8,10-diaza-bicyclo[4.3.1]decane derivatives, which are found to be cholinergic ligands at the nicotinic acetylcholine receptors. Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CNS), the peripheral nervous system (PNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or disorders related to neuro-degeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by the termination of abuse of chemical substances.

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