7H-Indolizino [5,6,7-IJ]isoquinoline derivatives

Details 7H-Indolizino [5,6,7-IJ]isoquinoline derivatives 7H-Indolizino [5,6,7-IJ]isoquinoline derivatives

1974-07-25

1976-03-23

Rollins, Alton D.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260283CN, 260 2835, 260286R, 260288D, 260288CF, 260289C, 2603478, 424258, C07D47116, C07D47118

Patent

active

039460193

ABSTRACT:
Compounds of the formula: ##SPC1##
Wherein R represents hydrogen, halogen or alkoxy of 1 to 4 carbon atoms, and R.sub.1 represents hydrogen, alkyl of 1 to 4 carbon atoms substituted by (i) carboxy, (ii) alkoxycarbonyl in which the alkoxy moiety contains 1 to 7 carbon atoms, or (iii) carbamoyl, or R.sub.1 represents phenylalkyl in which the alkyl moiety contains 1 to 4 carbon atoms and is substituted by (i) carboxy, (ii) alkoxycarbonyl in which the alkoxy moiety contains 1 to 4 carbon atoms, or (iii) carbamoyl, or R.sub.1 represents alkanoyl of 1 to 4 carbon atoms or benzoyl, are new compounds possessing chemotherapeutic properties and are particularly active as antibilharzial, anthelmintic and antimicrobial agents.

REFERENCES:
patent: 3784550 (1974-01-01), Yale
patent: 3793328 (1974-02-01), Hester

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