Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2003-04-03
2008-03-25
Schnizer, Richard (Department: 1635)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C800S003000, C536S024100, C435S325000, C435S354000
Reexamination Certificate
active
07348156
ABSTRACT:
In general, the invention features methods and uses for transposon-mediated gene targeting which greatly enhance the insertion and detection of desired genes in genomic exons by homologous recombination. The invention also features transgenic non-human mammals, and eukaryotic cells, wherein a gene encoding 7B2 protein is modified, as well as nucleic acid vectors capable of undergoing homologous recombination with an endogenous 7B2 gene in a cell. The invention also features transgenic non-human mammals as models of endocrine disorders, as well as methods for diagnosing and treating patients with endocrine disorders.
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Leder Philip
Lindberg Iris
Westphal Christoph H.
Board of Supervisors of Louisiana State University & Agricu
President and Fellows of Harvard College
Ropes & Gray LLP
Schnizer Richard
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