Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1997-02-19
1998-03-31
Powers, Fiona T.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514256, 514314, 514339, 514378, 514406, 544242, 544238, 544334, 544336, 548235, 5483647, 546152, 5462767, A61K 3141, A61K 3144, A61K 3150, C07D48708
Patent
active
057339120
ABSTRACT:
7a-Substituted hexahydro-1H-pyrrolizine compounds having the formula ##STR1## wherein A is a defined heterocycle moiety, pharmaceutical compositions of these compounds, and use of said compositions to selectively control synaptic transmission in mammals.
REFERENCES:
patent: 4582836 (1986-04-01), Carmosin et al.
patent: 4617401 (1986-10-01), Miyano et al.
patent: 4689329 (1987-08-01), Carmosin et al.
patent: 4800207 (1989-01-01), Carmosin et al.
patent: 4971975 (1990-11-01), Hadley et al.
patent: 5132316 (1992-07-01), Hadley et al.
patent: 5177084 (1993-01-01), Baker et al.
patent: 5217975 (1993-06-01), Wadsworth et al.
patent: 5242927 (1993-09-01), Baker et al.
patent: 5260293 (1993-11-01), Baker et al.
patent: 5260314 (1993-11-01), Sauerberg et al.
patent: 5262427 (1993-11-01), Nielson et al.
patent: 5472958 (1995-12-01), Gunn, Jr. et al.
patent: 5567710 (1996-10-01), Whitten et al.
patent: 5629325 (1997-05-01), Lin et al.
Reinecke et al, The Peripheral Synthesis of Medium Ring Nitrogen Heterycles Displacement Reactions; J. Org. Chem 37 No. 22 1972.
Leonard et al., Unsaturated Amines V. The Attack of Ternary Iminium Compounds by Nucleophilic Reagents; JACS, 78, 19, 1956.
Brioni et al., In Viv Profile of Novel Nicotinic Ligands with CNS Selectivity; Med Chem Res (1996) 487-510.
Badio et al., Antinociceptive Effects of the Alkaloid Epibatidine; Further Studies on Involvement of Nicotinic Receptors; Drug Develop. Research 36:46-59(1995).
Korczyn, Parkinson's Disease Psychopharmacology: The Fourth Generation of Progress, Raven Press, New York, 1995.
Roth et al., Biochemical Pharmacology of Midbrain Dopamine Neurons; Psychopharmacology: The Fourth Generation of Progress, Raven Press, New York, 1995.
Garvey David S.
Holladay Mark W.
Lin Nan-Horng
Ryther Keith B.
Wasicak James T.
Abbott Laboratories
Powers Fiona T.
Yang Frank Z.
LandOfFree
7A-heterocycle substituted hexahydro-1H-pyrrolizine compounds us does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with 7A-heterocycle substituted hexahydro-1H-pyrrolizine compounds us, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 7A-heterocycle substituted hexahydro-1H-pyrrolizine compounds us will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-52250