Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Reexamination Certificate
2005-05-31
2005-05-31
Housel, James (Department: 1645)
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
C424S200100, C424S190100, C424S185100, C424S184100, C536S023700, C536S024300, C435S069100, C435S069300, C435S252300
Reexamination Certificate
active
06899885
ABSTRACT:
A protein fromM. catarrhalis, designated the 74 kD protein, is isolated and purified. The 74 kD protein has an amino-terminal amino acid sequence which is conserved among various strains ofM. catarrhalis. The protein has a molecular weight of approximately 74.9 kD as measured on a 10% SDS-PAGE gel, while its molecular weight as measured by mass spectrometry is approximately 74 kD. The 74 kD protein is used to prepare a vaccine composition which elicits a protective immune response in a mammalian host, to protect the host against disease caused byM. catarrhalis.
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Barniak Vicki L.
Chen Dexiang
McMichael John C.
VanDerMeid Karl R.
Baskar Padma
Brazil Bill T.
Housel James
Wyeth Holdings Corporation
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