7-Ureido acetamido substituted cephalosporin antibiotics

Details 7-Ureido acetamido substituted cephalosporin antibiotics 7-Ureido acetamido substituted cephalosporin antibiotics

1975-03-03

1980-09-23

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Chalcogen in the nitrogen containing substituent

544 26, 544 28, 544 30, 424246, C07D50156, C07D50154, A61K 31545

Patent

active

042244420

ABSTRACT:
Cephalosporin antibiotics of the formula ##STR1## wherein R is ##STR2## and R" is H, C.sub.1 -C.sub.3 alkyl, allyl, propargyl, C.sub.3 -C.sub.6 cycloalkyl, phenyl, benzyl or furfuryl; R' is H or methyl; or R is a cyclic urea group for example, R is ##STR3## R.sub.1 is phenyl, thienyl, or furyl; R.sub.3 is a lower alkyl substituted 1H-tetrazole-5-thio or 1,3,4-thiadiazole-5-thio group and R.sub.4 is hydrogen or an active ester group, e.g., an acetoxymethyl group; are highly active broad spectrum antibiotics especially useful in the treatment of infections attributable to the gram-negative microorganisms.

REFERENCES:
patent: 3673183 (1972-06-01), Erickson
patent: 3687949 (1972-08-01), Holdrege
patent: 4086340 (1978-04-01), Schrock et al.
patent: 4093722 (1978-06-01), Schrock et al.
patent: 4107304 (1978-08-01), Schrock et al.

Affiliated with

Also associated with

Rating

7-Ureido acetamido substituted cephalosporin antibiotics does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 7-Ureido acetamido substituted cephalosporin antibiotics, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 7-Ureido acetamido substituted cephalosporin antibiotics will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-645453