7-sulfur substituted paclitaxels

Details 7-sulfur substituted paclitaxels 7-sulfur substituted paclitaxels

1998-04-14

2000-01-25

McKane, Joseph K.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514255, 514319, 514444, 514449, 514461, 5142328, 544107, 544374, 546196, 548525, 549 41, 549 60, 549511, A61K 31335, C07D26530, C07D29502, C07D30514

Patent

active

06017935&

ABSTRACT:
The present invention relates to novel taxane derivatives wherein, the taxol ring is substituted by sulfur groups on the C-7, their use as antitumor agents and pharmaceutical formulations.

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