7-Substituted methyl cephalosporins derivatives and analogues th

Details 7-Substituted methyl cephalosporins derivatives and analogues th 7-Substituted methyl cephalosporins derivatives and analogues th

1979-06-14

1981-10-20

Rizzo, Nicholas S.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

544 16, 544 21, 544 24, 544 22, C07D50100

Patent

active

042961114

ABSTRACT:
Disclosed are antibiotic 7-(substituted methyl) cephalosporins, derivatives and nuclear analogues thereof; wherein the methyl substituent is, inter alia, hydroxyl, ketonic oxygen, imino nitrogen, amino or thio. Also disclosed are processes for the preparation of such compounds and their pharmaceutically acceptable salt, ester and amide derivatives; pharmaceutical compositions comprising such compounds; and methods of treatment comprising administering such compounds and compositions when an antibiotic effect is indicated.

REFERENCES:
patent: 4123539 (1978-10-01), Dininno
patent: 4150156 (1979-04-01), Beattie

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