Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1978-05-08
1979-04-17
Daus, Donald G.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
544 17, 544 21, 544 22, 544 26, 544 27, 544 29, 544 90, 544282, 42424853, 424251, 424244, 260239A, 2603322H, A61K 31545, C07D50100
Patent
active
041501560
ABSTRACT:
Disclosed are antibiotic 3-(substituted thio)-7-(substituted methyl) cephalosporins, derivatives and analogues thereof; wherein the methyl substituent is, inter alia, hydroxyl, ketonic oxygen, imino nitrogen, amino or mercapto. Also disclosed are processes for the preparation of such compounds and their pharmaceutically acceptable salt, ester and amide derivatives; pharmaceutical compositions comprising such compounds; and methods of treatment comprising administering such compounds and compositions when an antibiotic effect is indicated.
REFERENCES:
patent: 3714156 (1973-06-01), Rapoport
patent: 3766177 (1973-10-01), Webber et al.
patent: 3976641 (1976-08-01), Hoover et al.
patent: 3992377 (1976-11-01), Chauvette et al.
patent: 4066641 (1978-01-01), Hamashima et al.
Beattie Thomas R.
Cama Lovji D.
Christensen Burton G.
DiNinno Frank P.
Arno James A.
Daus Donald G.
Levitt Julian S.
Mahon Frank M.
Merck & Co. , Inc.
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