7-substituted amino-1-aryl-6,8-difluoro-1,4-dihydro-4-oxo-3-quin

Details 7-substituted amino-1-aryl-6,8-difluoro-1,4-dihydro-4-oxo-3-quin 7-substituted amino-1-aryl-6,8-difluoro-1,4-dihydro-4-oxo-3-quin

1985-01-25

1986-10-14

Kepplinger, Esther M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514278, 546 15, 546 16, 546156, A61K 3197, C07D21527

Patent

active

046173080

ABSTRACT:
Novel 1-aryl or heteroaryl-6,8-difluoro-1,4-dihydro-7-(3-aminomethyl)pyrrolidinyl- or 7-spiroamino-4-oxo-3-quinolinecarboxylic acids and acid derivatives thereof as antibacterial agents are described as well as methods for their manufacture, formulation and use in treating bacterial infections caused by Gram-negative and Gram-positive bacteria.

REFERENCES:
patent: 4398029 (1983-08-01), Irikura
patent: 4530930 (1985-07-01), Uno
patent: 4550103 (1985-10-01), Mich
patent: 4550104 (1985-10-01), Mich

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