7-substituted-9-substituted amino-6-demethyl-6-deoxytetracycline

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – 3,10-dihydroxy-2-naphthacene carboxamide or derivative doai

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552203, 552205, 540200, 544154, 546195, 549487, 5482632, 5482676, 548538, 5483164, 5483004, 548358, 5483565, A61K 3165, C07C23364

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054949033

ABSTRACT:
The invention is drawn to 7-substituted-9-(substituted amino)-6-demethyl-6-deoxytetracycline compounds of the formula ##STR1## wherein R, X, R.sup.5 and R.sup.6 are defined in the specification. The compounds of the invention are useful as broad spectrum antibiotics.

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Chopra, Handbook of Experimental Parmacology, vol. 78, 317-392, Springer-Verlag (1985).
Levy, Antimicrobial Agents and Chemotherapy, vol. 33, No. 8, 1373-1374, (Aug. 1989).
Salyers, Molecular Microbiology 4(1), 151-156 (1990).

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