7-(Substituted)-7H-pyrrolo[3.2-F]-quinazoline-1,3-diamines

Organic compounds -- part of the class 532-570 series – Organic compounds – Four or more ring nitrogens in the bicyclo ring system

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C07D48704

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active

042334454

ABSTRACT:
7-(Substituted)-pyrrolo[3,2-f]quinazoline-1,3-diamines possess antibacterial activity in vitro. The invention also provides compounds having synergism in vivo with sulfa drugs against bacterial infections.

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DeGraw, et al., J. Med. Chem., vol. 17, pp. 762-764 (1974).
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Elslager, et al., J. Med. Chem, vol. 15, pp. 1138-1146 (1972).
Elslager, Progress in Drug Research, vol. 18, pp. 99-172 (1974).
Reed, et al., Amer. J. Hyg., vol. 27, pp. 493-497 (1938).

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