Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1995-03-01
1996-08-27
Berch, Mark L.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C07D491048, A61K 31395
Patent
active
055502300
ABSTRACT:
Disclosed is a novel .beta.-lactam compound, a 7-substituted-2-oxa-7-azabicyclo[3.2.0]heptan-6-one represented by the general formula ##STR1## in which R is an alkyl, cycloalkyl, aryl, halogen-substituted aryl or alkaryl group, having usefulness as an intermediate for the synthesis of various biologically active compounds. The compound can be prepared by the reaction of an isocyanate compound RNCO, R being the same as above, and 2,3-dihydrofuran, preferably, under pressurization up to 2000 atmospheres or higher.
Oishi Akihiro
Shibuya Isao
Taguchi Yoichi
Tsuchiya Tohru
Berch Mark L.
Japan as represented by Director General of Agency of Industrial
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