7-phenylalkyl substituted 2-quinolinones and...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C544S354000, C514S312000

Reexamination Certificate

active

07928104

ABSTRACT:
The present invention provides compounds of formula (I), their use as PARP inhibitors as well as pharmaceutical compositions comprising said compounds of formula (I)wherein n, R1, R2, R3, R4, R5, R6and X have defined meanings.

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Kulcsar et al., “Synthesis and Study of New 4-Quinazolinone Inhibitors of the DNA Repair Enzyme Poly (ADP-ribsose) Polymerase (PARP)”,ARKIVOC, XX,XX, Jun. 11, 2003, pp. 121-123, vol. 2003, No. Part V, XP002291367.
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PCT Intl. Search Report, PCT/EP2004/013162, Mar. 18, 2005.

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