7-phenyl-isoquinoline-5-sulfonylamino derivatives as...

Details 7-phenyl-isoquinoline-5-sulfonylamino derivatives as... 7-phenyl-isoquinoline-5-sulfonylamino derivatives as...

2004-11-22

2008-11-11

Davis, Zinna N (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S218000, C514S227800, C514S232800, C514S253050, C540S575000, C544S060000, C544S128000, C544S363000, C546S139000, C546S148000

Reexamination Certificate

active

07449477

ABSTRACT:
The present invention relates to compounds Formula (I) as inhibitors of AKT activity, which are useful for the treatment of susceptible neoplasms and viral infections.

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Reuveni, Hadas, et al., “Toward a PKB Inhibitor: Modification of a Selective PKA Inhibitor by Rational Design,” Biochemistry, vol. 41, No. 32, pp. 10304-10314 (2002); XP002267237.

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