7-oxo-PGI.sub.2 -ephedrine salts and their pharmaceutical compos

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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549465, A61K 31557, C07D307935

Patent

active

047359650

ABSTRACT:
The invention relates to new 7-oxo-PGI.sub.2 -ephedrine salt analogues of the Formula I ##STR1## wherein A stands for --(CH.sub.2).sub.2 --, cis or trans --CH.dbd.CH-- or --C.tbd.C--;

REFERENCES:
patent: 4330553 (1982-05-01), Simonidesz et al.
Merck Index, 8th Ed. (1968), pp. 409-410, and 10th Ed. (1983), p. 3555.
Oki et al., Bull. Chem. Soc. Japan, 43 (1970) pp. 2554-2558.
Kovacs et al, J. Med. Chem., 25(2) (1982) pp. 105-108.

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