Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...
Patent
1981-11-04
1984-10-02
Rizzo, Nicholas S.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Parasitic organism or component thereof or substance...
2602452R, 2602452T, 260239A, C07D49900, A61K 31425
Patent
active
044747934
ABSTRACT:
What are disclosed are compounds, useful as intermediates in the preparation of substituted penem compounds, of the formula ##STR1## methods for making such compounds from intermediates of the formula ##STR2## by reaction of the latter with a nucleophilic compound, methods for making such intermediates from compounds of the formula ##STR3## by reaction of the last-mentioned compounds with a tervalent phosphorus compound, and methods for making said last-mentioned compounds by cyclizing compounds of the formula ##STR4## with a tervalent phosphorus compound.
REFERENCES:
patent: 4290948 (1981-09-01), Brain et al.
patent: 4331676 (1982-05-01), Gosteli et al.
Chem. Abstr., 91, 193300h, (1979).
Johnson Graham
Ross Barry C.
Yeomans Michael A.
Hoechst U.K. Limited
Rizzo Nicholas S.
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