7-oxabicycloheptane substituted oxa prostaglandin analgos useful

Details 7-oxabicycloheptane substituted oxa prostaglandin analgos useful 7-oxabicycloheptane substituted oxa prostaglandin analgos useful

1984-09-24

1986-04-15

Jiles, Henry R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

549463, A61K 3134, A61K 31557, C07D30700

Patent

active

045828547

ABSTRACT:
7-Oxabicycloheptane substituted oxo prostaglandin analogs are provided having the structural formula ##STR1## wherein R is hydrogen, lower alkyl, alkali metal or trihydroxymethylaminomethane, R.sup.1 is lower alkyl, aryl, aralkyl, cycloalkyl or cycloalkylalkyl, R.sup.2 is hydrogen or lower alkyl, A is --CH.dbd.CH-- or --(CH.sub.2).sub.2 --, n is 1 to 4, and m is 1 to 8, and including all stereoisomers thereof.
The compounds are cardiovascular agents useful, for example, in the treatment of thrombolytic disease.

REFERENCES:
patent: 4143054 (1979-03-01), Sprague
patent: 4187236 (1980-02-01), Sprague
patent: 4220594 (1980-09-01), Sprague
patent: 4228180 (1980-10-01), Sprague
patent: 4254044 (1981-03-01), Sprague

Affiliated with

Also associated with

Rating

7-oxabicycloheptane substituted oxa prostaglandin analgos useful does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 7-oxabicycloheptane substituted oxa prostaglandin analgos useful, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 7-oxabicycloheptane substituted oxa prostaglandin analgos useful will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1439220