Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1994-04-20
1995-03-21
Lee, Mary C.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C07D30710, C07D31712
Patent
active
053997255
ABSTRACT:
A method is provided for preparing carboxylic acid intermediates of the structure ##STR1## wherein an aldehyde of the structure ##STR2## is prepared and subjected to a Horner-Emmons reaction to form the ester of the structure ##STR3## and the ester is hydrogenated to the carboxylic acid which may be used in making the final anti-thrombotic--anti-vasospastic compounds.
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Mueller Richard H.
Pansegrau Paul D.
Poss Michael A.
Singh Janak
Thottathil John K.
Bristol-Myers Squibb Co.
Lee Mary C.
McKane Joseph
Rodney Burton
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