7-Oxabicycloheptane- and 7-oxabicycloheptene compounds

Details 7-Oxabicycloheptane- and 7-oxabicycloheptene compounds 7-Oxabicycloheptane- and 7-oxabicycloheptene compounds

1980-03-07

1981-03-03

Jiles, Henry R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07D30700

Patent

active

042540445

ABSTRACT:
New compounds having the general formula ##STR1## are useful as cardiovascular agents, and as intermediates for the preparation of compounds having the general formula ##STR2## wherein R.sup.1 is hydrogen or lower alkyl; R.sup.2 is --CHO--, CH.sub.2 OH or --CH.dbd.CH--R.sup.3 --lower alkylene--CH.sub.3 ; and R.sub.3 is keto or hydroxymethyl.

REFERENCES:
Wlodawer et al., J.A.C.S. 93, 2815-2816 (1971).
Corey et al., J.A.C.S. 98, 6417-6418 (1976).
Bundy, Tetrahedron Letters 24, 1957-1960 (1975).
Rose et al., Proc. Soc. Exp. Biol. & Med. 153, 899-903 (1973).
Eggelte et al., Tetrahedron 29, 2445-2447 (1973).

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