7-oxabicyclo[2.2.1] heptane sulfonamide derivatives

Details 7-oxabicyclo[2.2.1] heptane sulfonamide derivatives 7-oxabicyclo[2.2.1] heptane sulfonamide derivatives

1989-03-23

1990-10-02

Lee, Mary C.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546269, C07D30700

Patent

active

049609092

ABSTRACT:
Bicyclic sulfonamido derivatives represented by the formula: ##STR1## wherein R.sub.1 is a hydrogen or lower alkyl; R.sub.2 is an alkyl, substituted or unsubstituted aryl, aralkyl or hetelocycle; R.sub.3 is a hydrogen or methyl; X is an alkylene or alkenylene which may be substituted by a fluorine atom or atoms and may contain an oxygen, sulfur and/or phenylene in the chain; Y is straight or branched alkylene or alkenylene oxygen, or sulfur; m is 0 or 1; and n is 0, 1 or 2, or their salt, said derivatives being useful as antithrombotic, anti-vasoconstricting, and anti-bronchoconstricting drugs.

REFERENCES:
patent: 4456616 (1984-06-01), Haslanger et al.
patent: 4654357 (1987-03-01), Nakane

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