7-methoxymethly-3-methyl-1-(5-oxohexyl)xanthine

Details 7-methoxymethly-3-methyl-1-(5-oxohexyl)xanthine 7-methoxymethly-3-methyl-1-(5-oxohexyl)xanthine

1995-06-07

1998-01-20

Berch, Mark L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Chalcogen bonded directly to ring carbon of the purine ring...

C07D47306, C07D47310

Patent

active

057102724

ABSTRACT:
A Rhodotorula rubra strain has been found which reduces pentoxifylline to 100% to give the S-alcohol. Moreover, other oxoalkylxanthine derivatives can also be convened into the corresponding S-alcohol. The microbiologically obtained S-(+)-enantiomers can then be converted stereoselectively into the respective R-(-)-enantiomers. The corresponding S-alcohols and the R-alcohols obtained by enantioselective inversion of configuration cause an increase in cerebral blood flow.

REFERENCES:
patent: 4833146 (1989-05-01), Gerbert et al.
Jones et al., Tetrahedron 42:3351-3403 (1986).
Davis et al., Xenobiotica 15(12):1001-1010 (1985).
ATCC Catalogue of Fungi/Yeasts 267 (1984).
Saucier et al., J. Biol. Chem. 264(12):6863-6869 (1989).
Smith et al., J. Chrom. 281:281-287 (1983).
Davis et al., Appl. Env. Microbiol. 48(2):327-331 (1984).

Affiliated with

Also associated with

Rating

7-methoxymethly-3-methyl-1-(5-oxohexyl)xanthine does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 7-methoxymethly-3-methyl-1-(5-oxohexyl)xanthine, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 7-methoxymethly-3-methyl-1-(5-oxohexyl)xanthine will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-726361