7-Hydroxylucanthone, 7-hydroxhycanthone and their analogs

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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544145, 544150, 544375, 546196, 546202, 548525, 549392, 514908, C07D31186, C07D33516

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active

045394121

ABSTRACT:
7-Hydroxylucanthone and 7-hydroxyhycanthone derivatives have been found to have significant antitumor effect. The derivatives are of the general formula: ##STR1## wherein the radicals R.sup.1 and R.sup.2 are lower alkyl groups or other simple groups and R.sup.3 is OH where X.dbd.O, and H or OH where X.dbd.S.

REFERENCES:
patent: 2627518 (1953-02-01), Archer
patent: 2631154 (1953-03-01), Archer
patent: 2653949 (1953-09-01), Archer
patent: 2653950 (1953-09-01), Archer
patent: 3294803 (1966-12-01), Rosi et al.
patent: 3711513 (1973-01-01), Schulenberg
Archer et al., JACS, vol. 74 (1952), pp. 4296-4308.

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