7-fluoroprostaglandins and process for their production

Details 7-fluoroprostaglandins and process for their production 7-fluoroprostaglandins and process for their production

1987-06-09

1989-04-18

Gerstl, Robert

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

556441, 549415, 549422, 549473, 549475, 560106, 560107, 560118, 560121, 560231, 562500, 562503, C07C17700

Patent

active

048229091

ABSTRACT:
7-Fluoroprostaglandins represented by the following formula (I): ##STR1## In the formula (I), R.sup.1 is a hydrogen atom or an alkyl group having from 1 to 10 carbon atoms, R.sup.2, R.sup.3 and R.sup.4 are hydrogen atoms or the same or different protective groups, respectively, and R.sup.5 is a straight chained, branched or cyclic alkyl group having from 3 to 7 carbon atoms.

REFERENCES:
patent: 4454339 (1984-06-01), Skuballa
Fieser et al, Reagents F Org. Syn. vol. 6 pp. 183-184 (1977) vol. 8 pp. 66-67 (1980).
Suzuki et al, Tet Letters 24 1187 (1983).
Riediker, J.A.C.S. 104 5842 (1982).

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