Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1982-09-07
1985-12-10
Jiles, Henry R.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
549214, 549305, 549415, C07D307935
Patent
active
045581428
ABSTRACT:
The prostacyclins 7-fluoro-6,9-epoxy-16-substituted-15-hydroxyprost-[4 or 5,13]-dienoic acids and esters useful as anti-secretory agents, blood pressure lowering agents, anti-ulcerogenic agents, anti-hypertensive agents, bronchodilation agents and for combating gastro-hyperacidity and as anti-blood platelet aggregating agents.
REFERENCES:
Fried et al., J. Med. Chem., 1980, 23, pp. 234-237.
Sukenick, J. Am. Chem. Soc., 1976, 98, pp. 6613-6623.
Corey et al., J. Am. Chem. Soc., 1977, 99, pp. 2006-2007.
Holland George W.
Maag Hans
Rosen Perry
Dentz Bernard I.
Epstein William H.
Gould George M.
Hoffmann-La Roche Inc.
Jiles Henry R.
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