7-disubstituted-methyl-4-oxo-3H,5H-pyrrolo[3,2d]pyrimidine and p

Details 7-disubstituted-methyl-4-oxo-3H,5H-pyrrolo[3,2d]pyrimidine and p 7-disubstituted-methyl-4-oxo-3H,5H-pyrrolo[3,2d]pyrimidine and p

1991-05-14

1993-02-23

Ford, John M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

5142342, 514253, 544117, 544232, 544238, 544244, 544280, 548535, 558404, A61K 31503, C07D47104

Patent

active

051890399

ABSTRACT:
Disclosed is a compound of the formula ##STR1## wherein R.sup.1 is H, NH.sub.2, or OCH.sub.3, R.sup.2 is an optionally substituted cyclic group optionally containing one or more heteroatoms, R.sup.3 and R.sup.4 are independently H or C.sub.1-4 alkyl, m is 0-4, n is 0-6, p is 0.1, X is CN, CSNH.sub.2, PO(OH).sub.2, COOH, SO.sub.2 NH.sub.2, NH.sub.2, OH, CNHNH.sub.2, tetrazole, triazole, or COR.sup.5 where R.sup.5 is C.sub.1-4 alkyl, CF.sub.3, NH.sub.2, or OC.sub.1-4 alkyl, and Y is O or NH that is useful as a pharmaceutical.

REFERENCES:
patent: 4772606 (1988-09-01), Sircar et al.
patent: 4923872 (1990-05-01), Kostlan et al.

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