7-Carboethoxy-morphinan-6-one compounds

Details 7-Carboethoxy-morphinan-6-one compounds 7-Carboethoxy-morphinan-6-one compounds

1982-06-10

1983-12-27

Rivers, Diana G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

424260, C07D22128, A61K 31485

Patent

active

044232217

ABSTRACT:
The present invention involves 7-carboethoxymorphinan-6-one compounds of the formula: ##STR1## These compounds are useful as analgesic and/or narcotic antagonists.

REFERENCES:
patent: 2178010 (1939-10-01), Small et al.
patent: 4347361 (1982-08-01), Quick et al.
patent: 4374139 (1983-02-01), Mohacsi
Quick et al., J. Med. Chem., vol. 25, No. 8, pp. 983-986 (8/82).
Herlihy et al., J. Med. Chem., vol. 25, No. 8, pp. 986-990 (8/82).
Kotick et al., J. Med. Chem., vol. 23, No. 2, pp. 166-174 (2/80).
Bentley & Hardy, Journal of the American Chemical Society, 89:13, pp. 3267-3273.
Rearick & Gates, Tetrahedron Letters, 507 (1970).
Sawa et al., Tetrahedron, 15, 144 (1961).
Leland et al., J. Med. Chem., 23, 1427 (1980).

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