7-bromomethyl-5-halo-8-hydroxyquinoline and method of preparatio

Details 7-bromomethyl-5-halo-8-hydroxyquinoline and method of preparatio 7-bromomethyl-5-halo-8-hydroxyquinoline and method of preparatio

1988-11-16

1990-10-02

Hollrah, Glennon H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546 90, 546180, C07D21528

Patent

active

049608932

ABSTRACT:
Halogenated hydroxyquinoline compounds such as 5-chloro-7-bromomethyl-8-hydroxyquinoline are prepared by contacting a 5-halo-8-hydroxyquinoline with formaldehyde to produce a cyclic dioxane and then contacting with concentrated hydrobromic acid to form the desired halogenated hydroxyquinoline compound.
The compounds of this invention are usefual as intermediates in the production of ion-exchange resins.

REFERENCES:
patent: 2681910 (1954-06-01), Burckhalter
patent: 2746963 (1956-05-01), Burckhalter
patent: 3391114 (1968-07-01), Schaefer et al.
patent: 3491100 (1970-01-01), Schaefer et al.
patent: 3560508 (1971-02-01), Ruhl et al.
patent: 4065455 (1977-12-01), Mattison
patent: 4520099 (1985-05-01), Akimura et al.
patent: 4631177 (1986-12-01), Yotsuyanagi et al.
Fernando et al., "Chemical Abstracts", vol. 51, 1957, Col. 5623b.
Zinner et al., "Reactions of Quinoline Derivatives with Formaldehyde", Arch Pharm., 291, No. 10, pp. 493-502 (1958).
Chem. Abstracts 3287a, vol. 71, 1969, p. 307, Swiss 465,958.
Chem. Abstracts 101:230364e, vol. 101, 1984, p. 755, JP 59,134,780.
Chem. Abstracts vol. 59, 1963, col. 7481, Ozawa et al., Yakugaku Zasshi 83, 498-502 (1963).
Chem. Abstracts vol. 60, 1964, Col. 10645-6, H. Fiedler, Arch. Pharm. 297(2), 108-117, 1964.
Derwent G6774, Jap. 15715/66.
Chem. Abstracts 3399z, vol. 80, 1974, p. 297, Fr. Demande 2,160,718.
Derwent 4099, Germ. 1,102,743.
Chem. Abstracts 100:220558m, vol. 100, 1984, p. 679, Uhlemann et al., Z. Anorg. Allg. Chem., 1984, 510, 79-87.
Chem. Abstracts 100:51428m, vol. 100, 1984, p. 567, Uhlemann et al., Z. Chem. 1983, 23(9), 334.
Derwent 11,681, Jap. 3843/64.
Chem. Abstracts 100:127563z, vol. 100, 1984, p. 410, Uhlemann et al., Anal. Chim. Acta 1984, 156,201-206.

Affiliated with

Also associated with

Rating

7-bromomethyl-5-halo-8-hydroxyquinoline and method of preparatio does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 7-bromomethyl-5-halo-8-hydroxyquinoline and method of preparatio, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 7-bromomethyl-5-halo-8-hydroxyquinoline and method of preparatio will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-293647