7.beta.-[[[2-Acylamino]-1,2-dioxoethyl]amino]acyl cephalosporins

Organic compounds -- part of the class 532-570 series – Organic compounds – Chalcogen in the nitrogen containing substituent

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544 4, 544 21, 544 22, 544 24, 544 25, 544 26, 544 28, 544 30, C07D50136, C07D50134, C07D50146, C07D50122

Patent

active

041699475

ABSTRACT:
7.beta.-[[[2-Acylamino]-1,2-dioxoethyl]amino]acyl cephalosporins of the formula ##STR1## wherein R is hydrogen, lower alkyl, phenyl-lower alkyl, diphenyl-lower alkyl, tri(lower alkyl)silyl, trihaloethyl or a salt forming ion; R.sub.1 is hydrogen, lower alkyl, saturated or unsaturated cycloalkyl, phenyl, phenyl-lower alkyl, substituted phenyl or certain heterocyclic groups; R.sub.2 is hydrogen or methoxy; R.sub.3 is hydrogen, lower alkyl or phenyl-lower alkyl; R.sub.4 is lower alkyl, cycloalkyl, phenyl, substituted phenyl or certain heterocyclic groups; and X is hydrogen, lower alkanoyloxy, carbamoyloxy, lower alkoxy, lower alkylthio, ##STR2## or certain heterothio groups, are useful as antibacterial agents.

REFERENCES:
patent: 4096330 (1978-06-01), Treuner et al.
patent: 4113943 (1978-09-01), Treuner et al.

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