7-Aminoalkyl-3,7-diaryl-3,3a,4,5,6,7-hexahydro-2H-indazoles

Details 7-Aminoalkyl-3,7-diaryl-3,3a,4,5,6,7-hexahydro-2H-indazoles 7-Aminoalkyl-3,7-diaryl-3,3a,4,5,6,7-hexahydro-2H-indazoles

1977-04-07

1978-04-18

Trousof, Natalie

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

548369, 2602936, 260268BC, 2605705CH, 42424856, 424250, 424267, 424273P, 542429, C07D23156, C07D40106, C07D41306

Patent

active

040852806

ABSTRACT:
Compounds having the formula ##STR1## and the pharmaceutically acceptable salts thereof, wherein R.sub.1 is alkylamino, dialkylamino or a nitrogen containing heterocyclic group; R.sub.2 and R.sub.3 are the same or different and are hydrogen, chloro, fluoro, alkyl, alkoxy or trifluoromethyl; R.sub.4 is hydrogen, alkyl, 2,2,2-trifluoroethyl, 2-hydroxyethyl, arylalkyl, or alkanoyl; and n is 1, 2 or 3; have useful anti-inflammatory activity.

REFERENCES:
patent: 3926988 (1975-12-01), Krapcho et al.
Chem. Absts., 84:30958v, (1976).

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