7-amino-3-(substituted isoindolinium)methyl-3-cephem derivatives

Details 7-amino-3-(substituted isoindolinium)methyl-3-cephem derivatives 7-amino-3-(substituted isoindolinium)methyl-3-cephem derivatives

1987-06-22

1989-11-28

Rizzo, Nicholas S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D50146, A61K 31545

Patent

active

048838683

ABSTRACT:
A compound having the formula: ##STR1## wherein R.sup.1 is an amino group or a protected amino group, R.sup.2 is a hydrogen atom or a protecting group for a hydroxyl group, R.sup.3 represents negative charge, a hydrogen atom or a protecting group for a carboxyl group, and n is 0 or 1, and a salt thereof.

REFERENCES:
patent: 4406899 (1983-09-01), Aburaki
patent: 4457929 (1984-07-01), Kamachi
patent: 4525473 (1985-06-01), Aburaki
patent: 4632918 (1980-12-01), Angerbauer
patent: 4677100 (1987-06-01), Nakagawa
Burger, A., Medicinal Chemistry, 2nd ed. (1960, Interscience Publishers, Inc.: New York), pp. 42-43.
McOmie, J., Protective Groups in Organic Chemistry, (1973, Plenum Press: New York), pp. 46-67, 157, 171-175.

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