7-Amino-3-(1-carboxymethyltetrazol-5-ylthiomethyl)-3-cephem-4-ca

Details 7-Amino-3-(1-carboxymethyltetrazol-5-ylthiomethyl)-3-cephem-4-ca 7-Amino-3-(1-carboxymethyltetrazol-5-ylthiomethyl)-3-cephem-4-ca

1976-08-05

1980-01-08

Rizzo, Nicholas S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Chalcogen in the nitrogen containing substituent

544 27, 424246, C07D50118

Patent

active

041828631

ABSTRACT:
Certain 7-acylamido-3-(1-carboxymethyltetrazol-5-ylthiomethyl)-3-cephem-4-carboxyl ic acids and their salts and easily hydrolyzed esters of the 4-carboxyl group were synthesized and found to be potent antibacterial agents which exhibited good aqueous solubility. In a preferred embodiment the 7-substituent was 2'-aminomethylphenylacetamido.

REFERENCES:
patent: 3819623 (1974-06-01), Takano et al.
patent: 3989694 (1976-11-01), Berges

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