7-amino-1-cyclopropyl-4-oxo-1, 4-dihydro-quinoline-and naphthyri

Details 7-amino-1-cyclopropyl-4-oxo-1, 4-dihydro-quinoline-and naphthyri 7-amino-1-cyclopropyl-4-oxo-1, 4-dihydro-quinoline-and naphthyri

1984-05-29

1987-06-02

Hollrah, Glennon H.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514236, 514254, 514312, 544127, 544128, 544295, 544362, 544363, 546123, 546156, A61K 31495, C07D52100

Patent

active

046704442

ABSTRACT:
The invention relates to 7-amino-1-cyclo-propyl-4-oxo-1, 4-dihydro-naphthyridine (or quinoline)-3-carboxylic acids of Formula I as defined in the specification. Also included in the invention is a process for the preparation of said compounds of Formula I and Ia. Further, the invention includes compositions containing the compounds of Formula I or Ia and the use of said compounds and compositions as antibacterial agents.

REFERENCES:
patent: 3849421 (1974-11-01), Nagagome et al.
patent: 4146719 (1979-03-01), Irikura
patent: 4284629 (1981-08-01), Grohe et al.
patent: 4292317 (1981-09-01), Pesson
patent: 4472579 (1984-09-01), Irikura et al.
patent: 4522819 (1985-06-01), Fox, Jr. et al.
patent: 4556709 (1985-12-01), Grohe et al.
Arzneimittelchemie I pp. 32-33, Georg Thieme Verlag Stuttgart, 1976.

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