7-amido-isoindolyl compounds and methods of their use

Details 7-amido-isoindolyl compounds and methods of their use 7-amido-isoindolyl compounds and methods of their use

2007-08-14

2007-08-14

McKane, Joseph K. (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C548S469000

Reexamination Certificate

active

11250408

ABSTRACT:
The invention encompasses 7-amido-isoindolyl compounds and methods of using these compounds and compositions in mammals for treatment, prevention or management of various diseases and disorders. Examples include, but are not limited to, cancer, inflammatory bowel disease and myelodysplastic syndrome.

REFERENCES:
patent: 6667316 (2003-12-01), Man et al.
patent: 6699899 (2004-03-01), Man et al.
patent: 7034052 (2006-04-01), Man et al.
Rice et al., 1989, Science 246: 1303-1306.
S.R. Grewe, J.M. Hanifin and S.C. Chan, 1982, J. Allergy & Clinical Imm., vol. 70, 199.6, pp. 452-457.
van Dullemen et al., 1995, Gastroenterology 109: 129-135.

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