7-(.alpha.-SUBSTITUTED GLYCINAMIDO)-3-SUBSTITUTED METHYL-3-CEPHE

Details 7-(.alpha.-SUBSTITUTED GLYCINAMIDO)-3-SUBSTITUTED METHYL-3-CEPHE 7-(.alpha.-SUBSTITUTED GLYCINAMIDO)-3-SUBSTITUTED METHYL-3-CEPHE

1975-03-28

1977-08-02

Rizzo, Nicholas S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Chalcogen in the nitrogen containing substituent

544 27, 424246, C07D50136

Patent

active

040395367

ABSTRACT:
This invention is concerned with 7-(.alpha.-substituted glycinamido)-3-substituted methyl-3-cephem-4-carboxylic acids, derivatives and non-toxic pharmaceutical salts thereof, which possess antibacterial activity, process for preparation thereof, having the following general formula ##STR1## wherein R.sub.1, R.sub.2, R.sub.3 and M are as defined hereinafter.

REFERENCES:
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patent: 3592812 (1971-07-01), Alburn et al.
patent: 3673183 (1972-06-01), Erickson
patent: 3796801 (1974-03-01), Guarini
patent: 3799923 (1974-03-01), Takano et al.
patent: 3840531 (1974-10-01), Greene
patent: 3864340 (1975-02-01), Ishimaru et al.
patent: 3867380 (1975-02-01), Dunn et al.
patent: 3966718 (1976-06-01), Brain et al.
patent: 3988450 (1976-10-01), James
Takano et al., "Chemical Abstracts," Abstract 124914m, vol. 71, 1969, p. 518.

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